• Pubmed Today 2026Jun09

    📅 2026년 6월 9일 | PubMed 수집 논문 ★ 주요 논문 — 이번 수집의 하이라이트 Survodutide in adults with obesity and metabolic dysfunction-associated steatotic liver disease: SYNCHRONIZE-MASLD, a randomized, double-blind, placebo-controlled phase 3 trial. Survodutide is a glucagon receptor/glucagon-like peptide-1 receptor dual agonist under investigation for treating obesity and related diseases. The SYNCHRONIZE-MASLD phase 3,…

  • Pubmed Today 2026Jun08

    📅 2026년 6월 8일 | PubMed 수집 논문 ★ 주요 논문 — 이번 수집의 하이라이트 High intrapancreatic fat deposition accelerates pancreatic ductal adenocarcinoma growth and metastasis with enrollment of FABP5 upregulation. A prospective observational study has shown that intrapancreatic fat deposition (IPFD) increases pancreatic ductal adenocarcinoma (PDAC) risk; however, the underlying mechanisms remain unclear. In…

  • Pubmed Today 2026Jun07

    📅 2026년 6월 7일 | PubMed 수집 논문 ★ 주요 논문 — 이번 수집의 하이라이트 Multi-omics and experimental evidence in human chondrocytes identify caspase-8 as a non-apoptotic regulator of inflammatory, senescent, and fibrotic signaling in osteoarthritis. Osteoarthritis (OA) is characterized by chronic inflammation, cellular senescence, and progressive cartilage remodeling, yet effective disease-modifying therapeutic targets remain…

  • Pubmed Today 2026Jun06

    📅 2026년 6월 6일 | PubMed 수집 논문 ★ 주요 논문 — 이번 수집의 하이라이트 HDAC inhibition reprograms stem cell fate to suppress infantile hemangioma vasculogenesis. Infantile hemangioma (IH), the most common vascular tumor of infancy, relies on hemangioma stem cells (HemSCs) to drive pathological vasculogenesis during the proliferating phase. While beta-blockers are currently first-line…

  • Pubmed Today 2026Jun05

    📅 2026년 6월 5일 | PubMed 수집 논문 ★ 주요 논문 — 이번 수집의 하이라이트 Continuous glucose monitoring versus self-monitoring of blood glucose in individuals with type 2 diabetes: a randomised, multicentre, open-label, superiority trial. Type 2 diabetes is the most common metabolic disorder worldwide, accounting for about 90% of people living with diabetes. Glycated…